High Blood Pressure (Hypertension) Affects 1 in 3 Adults Worldwide and About Half of Adults in the US1,2

over 70% with HBP have uncontrolled hypertension

Despite many treatment options, over 70% of people with high blood pressure in the US have uncontrolled hypertension.6

This is because their current treatment is not reducing their blood pressure to an acceptable level.

The ACC and ESH provide guidance about uncontrolled hypertension.

The American College of Cardiology and European Society of Hypertension provide guidance about uncontrolled hypertension, including treatment-resistant hypertension8,9

In general, people with treatment-resistant hypertension are those who are above blood pressure goals despite treatment with 3 or more antihypertensives, including treatment-resistant hypertension.8,9

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References: 1. World Health Organization. Global report on hypertension: the race against a silent killer. 2023. Available at: https://www.who.int/teams/noncommunicable-diseases/hypertension-report (Accessed May 2024). 2. Stierman B, et al. National Health and Nutrition Examination Survey 2017–March 2020 prepandemic data files—Development of files and prevalence estimates for selected health outcomes. National Health Statistics Reports; no 158. Hyattsville, MD: National Center for Health Statistics. 2021. DOI: https://dx.doi.org/10.
15620/cdc:106273. 3. Carey RM, et al. Hypertension. 2019;73(2):424-431. 4. Eurostat. Available at: https://ec.europa.eu/eurostat/web/products-eurostat-news/-/edn-20210929-1 (Accessed September 2024). 5. World Health Organization. Hypertension Japan 2023 country profile. Available at: https://www.who.int/publications/m/item/hypertension-jpn-2023-country-profile (Accessed July 2024). 6. Centers for Disease Control and Prevention (CDC). May 12, 2023. Available at: https://millionhearts.hhs.gov/data-reports/hypertension-prevalence.html (Accessed May 2024). 7. Brown JM, et al. Ann Intern Med. 2020;173(1):10-20. 8. Jones DW, et al. J Am Coll Cardiol. Published online August 8, 2025. doi: 10.1016/j.jacc.2025.05.007 9. Mancia G, et al. J Hypertens. 2023;41(12):1874-2071.